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. 2019 Jan;67(1):34-38.
doi: 10.1136/jim-2016-000263. Epub 2018 Oct 9.

Association between fine particulate matter and oral cancer among Taiwanese men

Yu-Hua Chu  1   2   3 , Syuan-Wei Kao  4 , Disline Manli Tantoh  4 , Pei-Chieh Ko  4 , Shou-Jen Lan  1   5 , Yung-Po Liaw  4   6
Affiliations

Association between fine particulate matter and oral cancer among Taiwanese men

Yu-Hua Chu et al. J Investig Med. 2019 Jan.

Abstract

The aim of this study was to investigate the association between fine particulate matter 2.5 (PM2.5) and oral cancer among Taiwanese men. Four linked data sources including the Taiwan Cancer Registry, Adult Preventive Medical Services Database, National Health Insurance Research Database, and Air Quality Monitoring Database were used. Concentrations of sulfur dioxide, carbon monoxide, ozone, NOx (nitrogen monoxide and nitrogen dioxide), coarse particulate matter (PM10-2.5) and PM2.5 in 2009 were assessed in quartiles. A total of 482 659 men aged 40 years and above were included in the analysis. Logistic regression was used to examine the association between PM2.5 and oral cancer diagnosed from 2012 to 2013. After adjusting for potential confounders, the ORs of oral cancer were 0.91 (95% CI 0.75 to 1.11) for 26.74≤PM2.5<32.37, 1.01 (95% CI 0.84 to 1.20) for 32.37≤PM2.5<40.37 µg/m3 and 1.43 (95% CI 1.17 to 1.74) for PM2.5≥40.37 µg/m3 compared with PM2.5<26.74 µg/m3 In this study, there was an increased risk of oral cancer among Taiwanese men who were exposed to higher concentrations of PM2.5.

Keywords: cancer; medical research; research.

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Conflict of interest statement

Competing interests: None declared.

Comment in

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