Review
doi: 10.1152/physiol.00027.2018.
Energy Constraint as a Novel Mechanism Linking Exercise and Health
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- PMID: 30303776
- DOI: 10.1152/physiol.00027.2018
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Review
Energy Constraint as a Novel Mechanism Linking Exercise and Health
Physiology (Bethesda).
.
Free article
Abstract
Humans and other species adapt dynamically to changes in daily physical activity, maintaining total energy expenditure within a narrow range. Chronic exercise thus suppresses other physiological activity, including immunity, reproduction, and stress response. This exercise-induced downregulation improves health at moderate levels of physical activity but can be detrimental at extreme workloads.
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