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Case Reports
. 2018 Oct 3;4(9):896-898.
doi: 10.1016/j.jdcr.2018.05.005. eCollection 2018 Oct.

Thalidomide as an effective treatment for adult multiple xanthogranuloma

Deborah Debois  1 , Liliane Marot  1   2 , Marc Andre  3 , Claire Dachelet  4
Affiliations
Case Reports

Thalidomide as an effective treatment for adult multiple xanthogranuloma

Deborah Debois et al. JAAD Case Rep. .
No abstract available

Keywords: XG, xanthogranulomatosis; adult multiple xanthogranuloma; myelodysplastic syndrome; non-Langerhans cells histiocytosis; thalidomide; xanthogranulomatosis.

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Figures

Fig 1
Fig 1
Skin examination finds well-demarcated, orange-reddish nodules of 0.5 to 1 cm with a firm to elastic consistency.
Fig 2
Fig 2
Punch biopsy result shows dense granulomatosis infiltrate composed mainly of histiocytes intermingled with collagen bundles, few neutrophils, eosinophils, and lymphocytes. (Hematoxylin-eosin stain; original magnification: ×20.)
Fig 3
Fig 3
Strong positive reaction to CD163.
Fig 4
Fig 4
Complete clearance of the skin lesions 3 weeks after the beginning of the treatment based on thalidomide (50 mg once a day), leaving only hyperpigmented macules.
See this image and copyright information in PMC

References

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