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. 2018 Nov;24(11):628-636.
doi: 10.1089/ten.TEC.2018.0151. Epub 2018 Nov 7.

Fibronectin and Collagen IV Microcontact Printing Improves Insulin Secretion by INS1E Cells

Elahe Hadavi  1 , Jeroen Leijten  1 , Jenny Brinkmann  2 , Pascal Jonkheijm  2 , Marcel Karperien  1 , Aart van Apeldoorn  1   3
Affiliations

Fibronectin and Collagen IV Microcontact Printing Improves Insulin Secretion by INS1E Cells

Elahe Hadavi et al. Tissue Eng Part C Methods. 2018 Nov.

Abstract

This research deals with finding a proper bioengineering strategy for the creation of improved β-cell replacement therapy in type 1 diabetes. It specifically deals with the microenvironment of β-cells and its relationship to their endocrine function.

Keywords: insulin secretion; islet transplantation; type 1 diabetes; β-cell replacement therapies; β-cells.

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