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. 2018 Oct 11;36(34):JCO1801097.
doi: 10.1200/JCO.18.01097. Online ahead of print.

Hypofractionated Radiation Therapy for Localized Prostate Cancer: An ASTRO, ASCO, and AUA Evidence-Based Guideline

Scott C Morgan  1 , Karen Hoffman  1 , D Andrew Loblaw  1 , Mark K Buyyounouski  1 , Caroline Patton  1 , Daniel Barocas  1 , Soren Bentzen  1 , Michael Chang  1 , Jason Efstathiou  1 , Patrick Greany  1 , Per Halvorsen  1 , Bridget F Koontz  1 , Colleen Lawton  1 , C Marc Leyrer  1 , Daniel Lin  1 , Michael Ray  1 , Howard Sandler  1
Affiliations

Hypofractionated Radiation Therapy for Localized Prostate Cancer: An ASTRO, ASCO, and AUA Evidence-Based Guideline

Scott C Morgan et al. J Clin Oncol. .
No abstract available

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Figures

Fig 1.
Fig 1.
(A) Rectal dose constraints from trials of moderate hypofractionation. (B) Bladder dose constraints from trials of moderate hypofractionation.
Fig 2.
Fig 2.
Examples of two methods of rectal contouring. The attached example prescribed to 6,000 cGy in 20 fractions compares the two methods of contouring the rectum in (A) the axial plane, (B) sagittal plane, and (C) representative DVH. The rectal sparing appears to be much greater using the CHHiP/RTOG 0415 method (orange) compared to the PROFIT method (yellow). If the CHHiP/RTOG 0415 contouring method were used with the PROFIT constraints, the rectum may be allowed to receive a greater dose than allowed on the PROFIT trial.
Fig 3.
Fig 3.
(A) Rectal dose constraints from trials of ultrahypofractionation. (B) Bladder dose constraints from trials of ultrahypofractionation.
See this image and copyright information in PMC

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