Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1987 Feb;20(2):286-91.
doi: 10.1227/00006123-198702000-00015.

Direct delivery of medication into a brain tumor through multiple chronically implanted catheters

G Bouvier, R D Penn, J S Kroin, R Beique, M J Guerard
Case Reports

Direct delivery of medication into a brain tumor through multiple chronically implanted catheters

G Bouvier et al. Neurosurgery. 1987 Feb.

Abstract

A recurrent malignant glioma was treated with cisplatin delivered directly into the tumor. The drug was delivered via 68 small catheters distributed evenly throughout the tumor area. Each catheter was connected to an osmotic minipump that delivered 0.5 microliter of drug solution each hour for 10 days. There were no side effects from the catheter implantation, chemotherapy, or catheter removal. Although the chemotherapy halted progression of the tumor, it recurred, and the patient died 6 months after treatment.

PubMed Disclaimer

Publication types