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Review
. 2018 Aug;13(4):285-291.
doi: 10.1159/000488189. Epub 2018 May 24.

Recent Developments in Radiation Oncology: An Overview of Individualised Treatment Strategies in Breast Cancer

Montserrat Pazos  1 , Stephan Schönecker  1 , Daniel Reitz  1 , Paul Rogowski  1 , Maximilian Niyazi  1 , Filippo Alongi  2   3 , Christiane Matuschek  4 , Michael Braun  5 , Nadia Harbeck  6 , Claus Belka  1 , Stefanie Corradini  1
Affiliations
Review

Recent Developments in Radiation Oncology: An Overview of Individualised Treatment Strategies in Breast Cancer

Montserrat Pazos et al. Breast Care (Basel). 2018 Aug.

Abstract

Radiation therapy (RT) for breast cancer has dramatically changed over the past years, leading to individualized risk-adapted treatment strategies. Historically, the choice of RT regimen was limited to conventional fractionation protocols using standard tangential fields. Nowadays, technological and technical improvements in modern RT have added a variety of other RT modalities, different fractionation schedules, and individualised treatment volumes to the portfolio of breast RT. This review aims to give a short overview on the main topics which have recently found their way into clinical practice: hypofractionated treatment protocols, accelerated partial breast irradiation (APBI) for low-risk patients, deep inspiration breath hold (DIBH) for maximal heart protection, extent of regional nodal irradiation for high-risk patients, and the implementation of new radiation techniques such as intensity modulated RT (IMRT) and volumetric modulated RT (VMAT).

Keywords: Breast cancer; Hypofractionation; Individualised therapy; Risk-adapted.

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