Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia
- PMID: 3032087
- PMCID: PMC174667
- DOI: 10.1128/AAC.31.1.121
Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia
Abstract
The measured outer membrane permeability of Pseudomonas cepacia to the beta-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.
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