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Review
. 2018 Oct 4:10:135-140.
doi: 10.2147/OARRR.S176666. eCollection 2018.

Novel treatments for osteoarthritis: an update

Yong Wu  1 , En Lin Goh  2 , Dong Wang  3 , Shaocheng Ma  3
Affiliations
Review

Novel treatments for osteoarthritis: an update

Yong Wu et al. Open Access Rheumatol. .

Abstract

Osteoarthritis is the most prevalent chronic joint condition worldwide. The principles of osteoarthritis treatment are to alleviate pain and stiffness as well as maintain function, with current consensus guidelines recommending the use of a combination of conservative measures including physical therapy, analgesia, and surgical interventions such as arthroplasty. In recent years, several pharmacological therapies have emerged as potential alternatives. Although a disease-modifying osteoarthritis drug has yet to be identified, promising results have been reported in recent trials especially with serotonin-norepinephrine reuptake inhibitors, IL-1 antagonists, and antibodies to nerve growth factor. The present review aims to summarize and discuss the latest results of novel treatments for osteoarthritis and potential targets for future research.

Keywords: future therapy; novel treatment; osteoarthritis; review.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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