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Randomized Controlled Trial
. 2018 Oct 16;13(10):e0201188.
doi: 10.1371/journal.pone.0201188. eCollection 2018.

Using web-based videos to improve inhalation technique in COPD patients requiring hospitalization: A randomized controlled trial

Affiliations
Randomized Controlled Trial

Using web-based videos to improve inhalation technique in COPD patients requiring hospitalization: A randomized controlled trial

Wolfram Windisch et al. PLoS One. .

Abstract

Background: Inhalation errors frequently occur in patients receiving inhalation treatment, which can significantly impair treatment success. While this underscores the importance of inhalation training, the role of modern web-based instructional videos has not yet been investigated.

Methods: A randomized controlled trial using standardized checklists (10 items: preparation, N = 3, inhalation routine, N = 6, and closure of inhalation, N = 1) was carried out to determine the relative effects of web-based, device-specific videos versus standard personal instruction on reducing multiple (≥2) inhalation errors in severe COPD patients requiring hospitalisation. Investigators assessing inhalation errors were blinded to the intervention.

Results: Multiple handling errors were recorded at baseline in 152 out of 159 patients (95.6%). Each teaching method led to a similar reduction in errors (videos: from 4.2±1.6 to 1.5±1.5 errors; personal instruction: from 3.8±1.5 to 1.3±1.6; p<0.0001), although non-inferiority of web-based video teaching could not be confirmed statistically due to an unpredictably high number of patients in both groups still making multiple handling errors (44.0% versus 40.3%, mean difference 3.7%; 95%CI [-12.0-19.4%]).

Conclusion: Multiple inhalation errors regularly occur in severe COPD patients requiring hospitalisation. Web-based video teaching is capable of reducing inhalation errors. However, compared to personal instruction non-inferiority could not be established. This was due to an unexpectedly high number of patients with persisting inhalation errors despite training.

Trial registration: Clinical trial Registration: German Clinical Trial Register, DRKS 00004320.

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Conflict of interest statement

WW, SBS, FSM, MD, JHS and VK received speaking fees and/or travel funding from different companies dealing with inhalation therapy. The authors state that none of the issues discussed in the submitted manuscript was dependent on or influenced by financial support. This does not alter our adherence to PLOS ONE policies on sharing data and materials.

Figures

Fig 1
Fig 1. Flowchart of the study design according to the CONSORT 2010 Statement [31].
Fig 2
Fig 2. Inhalation error rate at baseline and following teaching (N = 152).

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