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. 2018 Oct 16;13(10):e0205709.
doi: 10.1371/journal.pone.0205709. eCollection 2018.

The prevalence and risk factors of dyslipidemia in different diabetic progression stages among middle-aged and elderly populations in China

Yaru Li  1 , Liyun Zhao  1 , Dongmei Yu  1 , Gangqiang Ding  1
Affiliations

The prevalence and risk factors of dyslipidemia in different diabetic progression stages among middle-aged and elderly populations in China

Yaru Li et al. PLoS One. .

Abstract

Objectives: This study aimed to examine the prevalence and risk factors of dyslipidemia in different diabetic progression stages among middle-aged and elderly Chinese populations.

Methods: The 2010-2012 China National Nutrition and Health Survey (CNNHS) is a nationally representative cross-sectional study. In the present study, a total of 69,974 participants aged ≥ 45 years were included. Dyslipidemia was defined based on the Chinese adult dyslipidemia prevention guide. A multivariable logistic regression model was performed to examine the associations between risk factors and dyslipidemia.

Results: The prevalence of dyslipidemia was 39.9%, 46.8%, and 59.3% in participants with normal glucose, prediabetes, and type 2 diabetes mellitus (T2DM). Women had a lower dyslipidemia prevalence than men (38.7% vs. 43.3%). Dyslipidemia prevalence was positively associated with the education level and inversely correlated with the physical activity level, and negatively related to age only among prediabetes and T2DM groups (P for trend < 0.05). Obesity, abdominal obesity, and hypertension were associated with dyslipidemia.

Conclusions: The prevalence of dyslipidemia was relatively high among middle-aged and elderly T2DM person. There are different associations between multiple risk factors and dyslipidemia in different diabetic progression stages.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Prevalence of high TC, high TG, high LDL-C, low HDL-C, and dyslipidemia according to diabetic progression stages.
Abbreviations: TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; T2DM, type 2 diabetes mellitus.
See this image and copyright information in PMC

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