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Comparative Study
. 1987 Feb 10;134(2):233-7.
doi: 10.1016/0014-2999(87)90171-3.

Autoradiographic localisation of NPY receptors in rabbit kidney: comparison with rat, guinea-pig and human

K Leys, M Schachter, P Sever
Comparative Study

Autoradiographic localisation of NPY receptors in rabbit kidney: comparison with rat, guinea-pig and human

K Leys et al. Eur J Pharmacol. .

Abstract

In vitro labelling of neuropeptide Y binding sites with 125I-NPY was performed in rabbit kidney sections. Autoradiographic and histochemical techniques localised these binding sites to the proximal convoluted tubules and the vascular smooth muscle. In comparison, 125I-NPY binding was absent from the rat, guinea pig and human kidney. Possible physiological roles for the putative NPY receptors in rabbit renal function are discussed.

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