Thyroid Nodule DNA Methylation Signatures: An Important Diagnostic Annotation
- PMID: 30327307
- DOI: 10.1158/1078-0432.CCR-18-2820
Thyroid Nodule DNA Methylation Signatures: An Important Diagnostic Annotation
Abstract
Molecular profiling in thyroid cancer has made significant progress in part due to advances in somatic mutation profiling. Yet, differentiating benign from malignant thyroid nodules remains elusive. A unique set of DNA methylation signatures has the potential of improving thyroid cancer molecular diagnostics based on the DNA methylome.See related article by Yim et al., p. 544.
©2018 American Association for Cancer Research.
Comment on
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Identification of Tissue-Specific DNA Methylation Signatures for Thyroid Nodule Diagnostics.Clin Cancer Res. 2019 Jan 15;25(2):544-551. doi: 10.1158/1078-0432.CCR-18-0841. Epub 2018 Aug 9. Clin Cancer Res. 2019. PMID: 30093451 Free PMC article.
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