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Editorial
. 2018 Oct;30(10):2231-2232.
doi: 10.1105/tpc.18.00777. Epub 2018 Oct 16.

Inhibition of TOR, Nitrogen Assimilation, and Amino Acid Biosynthesis: Lessons from Chlamydomonas

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Editorial

Inhibition of TOR, Nitrogen Assimilation, and Amino Acid Biosynthesis: Lessons from Chlamydomonas

Jennifer Mach. Plant Cell. 2018 Oct.
No abstract available

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Inhibition of TOR increases nitrogen assimilation. In cells with active TOR, as part of the TORC1 complex, nitrogen import and assimilation occur normally. In cells where TORC1 function has been inhibited by rapamycin, increased nitrogen import (via the ammonium transporter AMT) and assimilation causes an increase in free amino acids. (Illustration courtesy of P. Giavalisco.)

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References

    1. Dobrenel T., Caldana C., Hanson J., Robaglia C., Vincentz M., Veit B., Meyer C. (2016). TOR signaling and nutrient sensing. Annu. Rev. Plant Biol. 67: 261–285. - PubMed
    1. Mubeen U., Jüppner J., Alpers J., Hincha D.K., Giavalisco P. (2018). Target of Rapamycin inhibition in Chlamydomonas reinhardtii triggers de novo amino acid synthesis by enhancing nitrogen assimilation. Plant Cell 30: 2240–2244. - PMC - PubMed

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