Cenabis Bene: Treg Cells Invite Macrophages to Dine

Lindsey D Hughes¹, Sourav Ghosh², Carla V Rothlin³

Affiliations

¹ Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06510, USA.
² Department of Neurology, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: sourav.ghosh@yale.edu.
³ Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: carla.rothlin@yale.edu.

PMID: 30332622
DOI: 10.1016/j.immuni.2018.10.002

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Cenabis Bene: Treg Cells Invite Macrophages to Dine

Lindsey D Hughes et al. Immunity. 2018.

Free article

. 2018 Oct 16;49(4):579-582.

doi: 10.1016/j.immuni.2018.10.002.

Authors

Lindsey D Hughes¹, Sourav Ghosh², Carla V Rothlin³

Affiliations

¹ Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06510, USA.
² Department of Neurology, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: sourav.ghosh@yale.edu.
³ Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: carla.rothlin@yale.edu.

PMID: 30332622
DOI: 10.1016/j.immuni.2018.10.002

Abstract

Resolution of the immune response requires a coordinated effort to dampen inflammatory mediators and remove dying cells and debris. In this issue of Immunity, Proto et al. (2018) describe a circuit by which regulatory T cells enhance macrophage consumption of apoptotic cells during resolution.

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Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution.
Proto JD, Doran AC, Gusarova G, Yurdagul A Jr, Sozen E, Subramanian M, Islam MN, Rymond CC, Du J, Hook J, Kuriakose G, Bhattacharya J, Tabas I. Proto JD, et al. Immunity. 2018 Oct 16;49(4):666-677.e6. doi: 10.1016/j.immuni.2018.07.015. Epub 2018 Oct 2. Immunity. 2018. PMID: 30291029 Free PMC article.

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Cenabis Bene: Treg Cells Invite Macrophages to Dine

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Cenabis Bene: Treg Cells Invite Macrophages to Dine

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