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Comment
. 2018 Oct 16;49(4):587-589.
doi: 10.1016/j.immuni.2018.10.004.

Lineage Specifiers in Lung Cancer Are Ahead of Their TIME

Kelli A Connolly  1 , Brittany Fitzgerald  1 , Nikhil S Joshi  2
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Lineage Specifiers in Lung Cancer Are Ahead of Their TIME

Kelli A Connolly et al. Immunity. .
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Abstract

The factors that shape the distinctive tumor-immune landscapes of various types and subtypes of cancer remain poorly understood. In this issue of Immunity, Mollaoglu et al. (2018) reveal a mechanistic link between the function of lineage specifiers SOX2 and NKX2-1 and the presence of neutrophils in the tumor-immune microenvironment of lung cancer.

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