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. 1987;10(1):62-5.
doi: 10.1007/BF01799489.

Regional distribution of the phenylalanine-sensitive ATP-sulphurylase in brain

K Matsuo, F Hommes

Regional distribution of the phenylalanine-sensitive ATP-sulphurylase in brain

K Matsuo et al. J Inherit Metab Dis. 1987.

Abstract

The regional distribution of the phenylalanine-sensitive ATP-sulphurylase in fetal calf brain coincides with demyelinated lesions observed in the central nervous systems of untreated PKU patients. This would be expected if this species of ATP-sulphurylase played a role in the pathogenesis of brain dysfunction in the untreated or poorly controlled phenylketonuria patient.

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