doi: 10.1002/mrm.1910040303.
In vivo 31P NMR spectroscopy of agonist-stimulated phosphatidylinositol metabolism in cat brain
- PMID: 3033424
- DOI: 10.1002/mrm.1910040303
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In vivo 31P NMR spectroscopy of agonist-stimulated phosphatidylinositol metabolism in cat brain
Magn Reson Med.
1987 Mar.
Abstract
As a result of the agonist stimulation of muscarinic receptors, myo-inositol-1-phosphate accumulates in the presence of millimolar lithium concentrations. This accumulation of myo-inositol-1-phosphate can be detected by in vivo 31P NMR spectroscopy. Since myo-inositol-1-phosphate is a breakdown product of phosphatidylinositol, this may provide a means of noninvasively monitoring phosphatidylinositol metabolism in vivo.
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