Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Nov;24(11):2036-2040.
doi: 10.3201/eid2411.180368.

Candida auris in South Africa, 2012-2016

Nelesh P Govender, Rindidzani E Magobo, Ruth Mpembe, Mabatho Mhlanga, Phelly Matlapeng, Craig Corcoran, Chetna Govind, Warren Lowman, Marthinus Senekal, Juno Thomas

Candida auris in South Africa, 2012-2016

Nelesh P Govender et al. Emerg Infect Dis. 2018 Nov.

Abstract

To determine the epidemiology of Candida auris in South Africa, we reviewed data from public- and private-sector diagnostic laboratories that reported confirmed and probable cases of invasive disease and colonization for October 2012-November 2016. We defined a case as a first isolation of C. auris from any specimen from a person of any age admitted to any healthcare facility in South Africa. We defined probable cases as cases where the diagnostic laboratory had used a nonconfirmatory biochemical identification method and C. haemulonii was cultured. We analyzed 1,692 cases; 93% were from private-sector healthcare facilities, and 92% of cases from known locations were from Gauteng Province. Of cases with available data, 29% were invasive infections. The number of cases increased from 18 (October 2012-November 2013) to 861 (October 2015-November 2016). Our results show a large increase in C. auris cases during the study period, centered on private hospitals in Gauteng Province.

Keywords: Candida; Candida auris; South Africa; fungi; laboratory surveillance; yeast.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Distribution of cases of Candida auris by type of infection, South Africa, 2012–2016. Data are from the top 20 private hospitals that reported cases. n = 1,087.
Figure 2
Figure 2
Distribution of cases of Candida auris by type of infection and date of specimen collection, South Africa, 2012–2016. n = 1,306.
See this image and copyright information in PMC

References

    1. Magobo RE, Corcoran C, Seetharam S, Govender NP. Candida auris-associated candidemia, South Africa. Emerg Infect Dis. 2014;20:1250–1. 10.3201/eid2007.131765 - DOI - PMC - PubMed
    1. Jeffery-Smith A, Taori SK, Schelenz S, Jeffery K, Johnson EM, Borman A, et al.; Candida auris Incident Management Team. Candida auris Incident Management Team. Candida auris: a review of the literature. Clin Microbiol Rev. 2017;31:e00029–17. 10.1128/CMR.00029-17 - DOI - PMC - PubMed
    1. Escandón P, Chow NA, Caceres DH, Gade L, Berkow EL, Armstrong P, et al. Molecular epidemiology of Candida auris in Colombia reveals a highly-related, country-wide colonization with regional patterns in Amphotericin B resistance. Clin Infect Dis. 2018. 10.1093/cid/ciy411 - DOI - PubMed
    1. Sherry L, Ramage G, Kean R, Borman A, Johnson EM, Richardson MD, et al. Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris. Emerg Infect Dis. 2017;23:328–31. 10.3201/eid2302.161320 - DOI - PMC - PubMed
    1. Ku TSN, Walraven CJ, Lee SA. Candida auris: disinfectants and implications for infection control. Front Microbiol. 2018;9:726. 10.3389/fmicb.2018.00726 - DOI - PMC - PubMed