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Clinical Trial

Detection and Characterization of Human Pegivirus 2, Vietnam

Nguyen To Anh et al. Emerg Infect Dis. 2018 Nov.

Abstract

We report human pegivirus 2 (HPgV-2) infection in Vietnam. We detected HPgV-2 in some patients with hepatitis C virus/HIV co-infection but not in patients with HIV or hepatitis A, B, or C virus infection, nor in healthy controls. HPgV-2 strains in Vietnam are phylogenetically related to global strains.

Keywords: HCV; HIV; Vietnam; hepatitis and sepsis; human hepegivirus 1; human pegivirus 2; viruses.

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Figures

Figure
Figure
Maximum-likelihood phylogenetic tree of amino acid sequences of coding sequences of human pegivirus 2 strains from Vietnam compared with global strains and other pegiviruses. We used the general matrix with empirical amino acid frequencies, a gamma distribution of 4 rates, and invariant sites, as suggested by IQ TREE (http://www.iqtree.org), to reconstruct the phylogenetic trees. We assessed support for individual nodes using a bootstrap procedure of 10,000 replicates. Scale bar indicates amino acid substitutions per site.
See this image and copyright information in PMC

References

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