The molecular structure of opiate receptors

Abstract

Examples are given which demonstrate that the kappa opiate receptor can be separated from mu and delta subtypes by their physical parameters. When the subunit composition of the subtypes are compared, no definite differences are encountered. The data from the literature are also contradictory. This may in part be explained by the fact that the different receptors appear to contain a structurally common high affinity binding site. A possible hypothesis would be that the subtypes differ from each other by the number of subunits.