Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Esophageal Perforation and Tears

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Esophageal Perforation and Tears

Mohammed M. Kassem et al.
Free Books & Documents

Excerpt

Esophageal perforations and tears present a significant and complex challenge for the therapeutic team, necessitating an interprofessional approach for successful management. These injuries can occur in 3 distinct anatomical compartments—cervical, thoracic, and abdominal—each with a range of often nonspecific symptoms. This variability in presentation can lead to significant delays in diagnosis, complicating the management of the condition. Despite advancements in diagnostic technologies and therapeutic strategies, esophageal perforations and tears remain life-threatening, with mortality rates reaching up to 50%.

The incidence of esophageal perforation in the United States is approximately 3 per 100,000 individuals, with intrathoracic perforations being the most common, accounting for 54% of cases. Cervical esophageal perforations follow at 27%, while intraabdominal perforations comprise 19%. Iatrogenic causes, particularly those related to endoscopic procedures, are the leading contributors to esophageal perforation, responsible for 59% of cases. In contrast, traumatic external injuries rarely result in esophageal perforation; however, when foreign objects are involved, fish bones are the most frequent cause, accounting for 12% of cases.

The concurrence of esophageal perforation and mediastinal abscesses is relatively rare, but when it occurs, it can lead to severe complications such as thoracic abscess, sepsis, and septic shock, with mortality rates as high as 66%. The critical importance of prompt identification and diagnosis cannot be overstated, as studies show that delays in diagnosis significantly increase mortality rates. Treatment strategies for esophageal perforations, particularly those complicated by mediastinal abscesses, often involve surgical intervention or drainage, underscoring the need for a timely and coordinated therapeutic approach.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Mohammed Kassem declares no relevant financial relationships with ineligible companies.

Disclosure: Jason Wallen declares no relevant financial relationships with ineligible companies.

References

    1. Younes Z, Johnson DA. The spectrum of spontaneous and iatrogenic esophageal injury: perforations, Mallory-Weiss tears, and hematomas. J Clin Gastroenterol. 1999 Dec;29(4):306-17. - PubMed
    1. White RK, Morris DM. Diagnosis and management of esophageal perforations. Am Surg. 1992 Feb;58(2):112-9. - PubMed
    1. Badertscher P, Delko T, Oertli D, Reuthebuch O, Schurr U, Pradella M, Kühne M, Sticherling C, Osswald S. Surgical repair of an esophageal perforation after radiofrequency catheter ablation for atrial fibrillation. Indian Pacing Electrophysiol J. 2019 May-Jun;19(3):110-113. - PMC - PubMed
    1. Dudzinski DM, Mangalmurti SS, Oetgen WJ. Characterization of Medical Professional Liability Risks Associated With Transesophageal Echocardiography. J Am Soc Echocardiogr. 2019 Mar;32(3):359-364. - PubMed
    1. Zhong S, Wu Z, Wang Z. Successful Treatment of Fishbone-Induced Esophageal Perforation and Mediastinal Abscess: A Case Report and Literature Review. Am J Case Rep. 2023 Dec 18;24:e942056. - PMC - PubMed

Publication types

LinkOut - more resources