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Case Reports
. 2018 Sep 24;6(9):1697-1698.
doi: 10.3889/oamjms.2018.403. eCollection 2018 Sep 25.

Multinodular and Vacuolating Neuronal Tumor

Charmaine Zahra  1 , Reuben Grech  1
Affiliations
Case Reports

Multinodular and Vacuolating Neuronal Tumor

Charmaine Zahra et al. Open Access Maced J Med Sci. .

Abstract

Background: Multinodular and Vacuolating Neuronal Tumor (MVNT) of the cerebrum is a benign lesion described recently in the WHO CNS tumours in 2016. Although this tumour is uncommon, clinicians should be acquainted with the possible presentation and imaging findings.

Case report: We present a case of a young gentleman whose only symptom was absence seizures. Brain imaging showed lesions, compatible with this rare diagnosis.

Conclusion: Our description of imaging findings on MRI highlights the characteristic cystic appearances of note in the right occipital lobe, in contrast to the temporal lobe as the predominant location found in previous cases.

Keywords: CNS tumours; DWI; FLAIR; MRI; MVNT.

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Figures

Figure 1
Figure 1
(A) T2-weighted (B) T1-weighted and (C) Fluid-attenuated inversion recovery (FLAIR) MRI. There are multiple well-defined cortical-based lesions. These appear hyperintense on T2-weighted and FLAIR imaging and are hypointense on T1-weighted sequences. No associated vasogenic oedema or mass effect is seen
Figure 2
Figure 2
(A) Diffusion-weighted Imaging and (B) contrast enhanced T1 weighted sequences. The lesion does not restrict diffusion, and there is no pathological contrast uptake
See this image and copyright information in PMC

References

    1. Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System:a summary. Acta Neuropathol. 2016;131:803–820. https://doi.org/10.1007/s00401-016-1545-1 PMid:27157931. - PubMed
    1. Nunes RH, Hsu CC2, da Rocha AJ, et al. Multinodular and Vacuolating Neuronal Tumor of the Cerebrum:A New “Leave Me Alone” Lesion with a Characteristic Imaging Pattern. AJNR Am J Neuroradiol. 2017 - PMC - PubMed
    1. Huse JT, Edgar M, Halliday J, Mikolaenko I, Lavi E, Rosenblum MK. Multinodular and vacuolating neuronal tumours of the cerebrum:10 cases of a distinctive seizure-associated lesion. Brain Pathol. 2013;23:515–24. https://doi.org/10.1111/bpa.12035 PMid:23324039. - PMC - PubMed

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