Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Oct 18;19(12):99.
doi: 10.1007/s11934-018-0854-4.

Optimizing Nutrition Prior to Radical Cystectomy

Anthony D Oberle  1 , Jeremy M West  1 , Conrad M Tobert  1 , Gabriel L Conley  1 , Kenneth G Nepple  2
Affiliations
Review

Optimizing Nutrition Prior to Radical Cystectomy

Anthony D Oberle et al. Curr Urol Rep. .

Abstract

Purpose of review: Malnutrition in a prevalent problem in patients undergoing radical cystectomy. Preoperative malnutrition has been shown to contribute to increased rates of postoperative complications. Given the significant morbidity and mortality of the procedure of radical cystectomy, there is potential for improvement in patient outcomes by nutritional intervention.

Recent findings: Prospective studies have demonstrated a reduction in postoperative infection rates in patients who receive supplemental immunonutrition prior to major surgery including radical cystectomy. These initial evaluations of nutritional optimization show significant potential for improved outcomes. Additionally, several studies using enhanced recovery after surgery protocols, which include a preoperative nutritional component, have shown a benefit in reducing length of stay. Emerging literature has shown the benefits of preoperative immunonutrition in improving postoperative outcomes of radical cystectomy. However, further work is needed to determine the best mechanism to optimize nutrition prior to radical cystectomy.

Keywords: Bladder cancer; Cystectomy; Malnutrition; Nutrition.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Anthony D. Oberle, Jeremy M. West, Conrad M. Tobert, Gabriel L. Conley, and Kenneth G. Nepple each declare no potential conflicts of interest.

References

    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30. - PubMed
    1. Smith AB,Deal AM, Woods ME,Wallen EM, Pruthi RS,Chen RC, et al. Muscle-invasive bladder cancer: evaluating treatment and survival in the National Cancer Data Base. BJU Int. 2014;114(5): 719–26. - PubMed
    1. Witjes JA, Compérat E, Cowan NC, De Santis M, Gakis G, Lebret T, et al. EAU guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2013 guidelines. Eur Urol. 2014;65(4): 778–92. - PubMed
    1. Bochner BH, Dalbagni G, Sjoberg DD, Silberstein J, Keren Paz GE, Donat SM, et al. Comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy: a randomized clinical trial. Eur Urol. 2015;67(6):1042–50. - PMC - PubMed
    1. Comploj E, West J, Mian M, Kluth LA, Karl A, Dechet C, et al. Comparison of complications from radical cystectomy between old-old versus oldest-old patients. Urol Int. 2015;94(1):25–30. - PubMed