doi: 10.1213/00000539-197807000-00019.
Effects of pH on protein binding of lidocaine
- PMID: 30342
- DOI: 10.1213/00000539-197807000-00019
Item in Clipboard
Effects of pH on protein binding of lidocaine
Anesth Analg.
1978 Jul-Aug.
Abstract
Protein binding of lidocaine (2.5, 5, 10, and 20 microgram/ml in fresh plasma was studied from pH 5.6 to pH 9.8. Percent binding of lidocaine was inversely related to hydrogen-ion and lidocaine concentrations.
Similar articles
-
[The influence of different volatile inhaled anesthetics on the plasma protein binding of lidocaine].Masui. 1991 Mar;40(3):421-30. Masui. 1991. PMID: 2072495 Japanese.
-
BUFFER-DEMAND AND PH OF LOCAL ANESTHETIC SOLUTIONS CONTAINING EPINEPHRINE.Anesthesiology. 1963 Nov-Dec;24:801-7. doi: 10.1097/00000542-196311000-00009. Anesthesiology. 1963. PMID: 14071412 No abstract available.
-
Factors influencing serum protein binding of lidocaine in humans.Anesth Analg. 1981 Jun;60(6):395-400. Anesth Analg. 1981. PMID: 6165258
-
Dependence of lung uptake of lidocaine in vivo on blood pH.Acta Pharmacol Toxicol (Copenh). 1982 Aug;51(2):136-40. doi: 10.1111/j.1600-0773.1982.tb01004.x. Acta Pharmacol Toxicol (Copenh). 1982. PMID: 7113720
-
Comparison of pH-adjusted lidocaine solutions for epidural anesthesia.Anesth Analg. 1986 Jul;65(7):760-4. Anesth Analg. 1986. PMID: 3717616
Cited by
-
Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study.Emerg (Tehran). 2018;6(1):e35. Epub 2018 Jun 5. Emerg (Tehran). 2018. PMID: 30009237 Free PMC article.
-
Pethidine binding in plasma: effects of methodological variables.Br J Clin Pharmacol. 1984 Apr;17(4):411-5. doi: 10.1111/j.1365-2125.1984.tb02365.x. Br J Clin Pharmacol. 1984. PMID: 6721987 Free PMC article.
-
Plasma protein binding of etidocaine during pregnancy and labour.Eur J Clin Pharmacol. 1982;22(5):451-7. doi: 10.1007/BF00542552. Eur J Clin Pharmacol. 1982. PMID: 7117359
-
[Lipid emulsion therapy for local anaesthetic toxicity. (LipidRescue)].Anaesthesist. 2010 Jun;59(6):575-83; quiz 584-6. doi: 10.1007/s00101-010-1724-8. Anaesthesist. 2010. PMID: 20490441 Review. German.
-
Clinical features, pathogenesis and management of drug-induced seizures.Drug Saf. 1990 Mar-Apr;5(2):109-51. doi: 10.2165/00002018-199005020-00004. Drug Saf. 1990. PMID: 2182049 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
