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. 2019 Feb:205:277-280.
doi: 10.1016/j.jpeds.2018.09.046. Epub 2018 Oct 17.

Umbilical Cord Tissue and Meconium May Not Be Equivalent for Confirming in Utero Substance Exposure

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Umbilical Cord Tissue and Meconium May Not Be Equivalent for Confirming in Utero Substance Exposure

Jennifer M Colby et al. J Pediatr. 2019 Feb.

Abstract

In a retrospective study of 501 neonates with potential in utero substance exposure, the drug detection performance of a commercially available umbilical cord tissue toxicology test was evaluated against a commercially available gold standard meconium toxicology test. Drugs detected in paired meconium and umbilical cord tissue samples were often discordant.

Keywords: drug screening; in utero drug exposure; meconium; toxicology; umbilical cord tissue.

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