Umbilical Cord Tissue and Meconium May Not Be Equivalent for Confirming in Utero Substance Exposure
- PMID: 30342870
- PMCID: PMC6348119
- DOI: 10.1016/j.jpeds.2018.09.046
Umbilical Cord Tissue and Meconium May Not Be Equivalent for Confirming in Utero Substance Exposure
Abstract
In a retrospective study of 501 neonates with potential in utero substance exposure, the drug detection performance of a commercially available umbilical cord tissue toxicology test was evaluated against a commercially available gold standard meconium toxicology test. Drugs detected in paired meconium and umbilical cord tissue samples were often discordant.
Keywords: drug screening; in utero drug exposure; meconium; toxicology; umbilical cord tissue.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment in
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Testing umbilical cord tissue for drugs: Lower analytical limits, better concordance with meconium results.J Pediatr. 2019 Jun;209:258-259. doi: 10.1016/j.jpeds.2019.01.009. Epub 2019 Feb 2. J Pediatr. 2019. PMID: 30723018 No abstract available.
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Reply.J Pediatr. 2019 Jun;209:259. doi: 10.1016/j.jpeds.2019.02.026. Epub 2019 Mar 27. J Pediatr. 2019. PMID: 30928145 No abstract available.
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