Review

. 2018 Oct 21;5(4):112.

doi: 10.3390/medicines5040112.

Antioxidant, Antifungal, Antibiofilm, and Cytotoxic Activities of Mentha spp. Essential Oils

Annarita Stringaro¹, Marisa Colone², Letizia Angiolella³

Affiliations

¹ National Center for Drug Research and Evaluation, Italian National Institute of Health, Viale Regina Elena, 299, 00161 Rome, Italy. annarita.stringaro@iss.it.
² National Center for Drug Research and Evaluation, Italian National Institute of Health, Viale Regina Elena, 299, 00161 Rome, Italy. marisa.colone@iss.it.
³ Department of Public Health and Infectious Diseases, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy. letizia.angiolella@uniroma1.it.

PMID: 30347861
PMCID: PMC6313564
DOI: 10.3390/medicines5040112

Review

Antioxidant, Antifungal, Antibiofilm, and Cytotoxic Activities of Mentha spp. Essential Oils

Annarita Stringaro et al. Medicines (Basel). 2018.

. 2018 Oct 21;5(4):112.

doi: 10.3390/medicines5040112.

Authors

Annarita Stringaro¹, Marisa Colone², Letizia Angiolella³

Affiliations

¹ National Center for Drug Research and Evaluation, Italian National Institute of Health, Viale Regina Elena, 299, 00161 Rome, Italy. annarita.stringaro@iss.it.
² National Center for Drug Research and Evaluation, Italian National Institute of Health, Viale Regina Elena, 299, 00161 Rome, Italy. marisa.colone@iss.it.
³ Department of Public Health and Infectious Diseases, Sapienza University of Rome, P.le Aldo Moro, 5, 00185 Rome, Italy. letizia.angiolella@uniroma1.it.

PMID: 30347861
PMCID: PMC6313564
DOI: 10.3390/medicines5040112

Abstract

Since ancient times, plants have been used to preserve food, or for their health properties. Essential oils are complex mixtures of volatile compounds that are obtained from botanical material, specifically from aromatic plants. Lamiaceae is one of the most important families in the production of essential oils, as it has both antioxidant and antimicrobial properties. The essential oils of Mentha (the Lamiaceae family) have been extensively studied for their biological actions. In this review, we report the antioxidant, antifungal, antibiofilm, and cytotoxic properties of Mentha spp. essential oils. The first objective is to provide comprehensive information about the use of essential oils in the treatment of fungal infections, or as antioxidants and integrative anticancer therapy. The second is to explore the evidence supporting its effectiveness in treating diseases without causing any serious adverse reactions.

Keywords: Mentha spp.; antibiofilm; antifungal; antioxidant; essential oil; toxicity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

**Figure 1**
Chemical structures of the main components of *Mentha* spp. essential oils (EOs).

**Figure 2**
Scanning electron microscopy image of SKBR3 cells (a) (5 μm) and incubated with *Mentha suaveolens* EO for 24 h (b).

See this image and copyright information in PMC

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References

1. Prabuseenivasan S., Jayakumar M., Ignacimuthu S. In vitro antibacterial activity of some plant essential oils. BMC Complement. Altern. Med. 2006;6:39–50. doi: 10.1186/1472-6882-6-39. - DOI - PMC - PubMed
1. Aburjai T., Natsheh F.M. Plants used in cosmetics. Phytother. Res. 2003;17:987–1000. doi: 10.1002/ptr.1363. - DOI - PubMed
1. Wallace R.J. Antimicrobial properties of plant secondary metabolites. Proc. Nutr. Soc. 2004;63:621–629. doi: 10.1079/PNS2004393. - DOI - PubMed
1. Bakkali F., Averbeck S., Averbeck D., Idaomar M. Biological effects of essential oils—A review. Food Chem. Toxicol. 2008;46:446–475. doi: 10.1016/j.fct.2007.09.106. - DOI - PubMed
1. Nakatsu T., Lupo A.T., Chinn J.W., Kang R.K.L. Studies in Natural Products Chemistry. Volume 21. Elsevier; New York, NY, USA: 2000. pp. 571–631.

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Antioxidant, Antifungal, Antibiofilm, and Cytotoxic Activities of Mentha spp. Essential Oils

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Antioxidant, Antifungal, Antibiofilm, and Cytotoxic Activities of Mentha spp. Essential Oils

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Abstract

Conflict of interest statement

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