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Review
. 2019 Jan 15:192:500-507.
doi: 10.1016/j.talanta.2018.08.086. Epub 2018 Sep 4.

The detection of mercury ion using DNA as sensors based on fluorescence resonance energy transfer

Ni Xia  1 , Fan Feng  2 , Cheng Liu  1 , Raoqi Li  1 , Wenwen Xiang  1 , Haixia Shi  3 , Li Gao  4
Affiliations
Review

The detection of mercury ion using DNA as sensors based on fluorescence resonance energy transfer

Ni Xia et al. Talanta. .

Abstract

Mercury ion (Hg2+) is a heavy metal that can cause serious water pollution. With the accumulation of large quantities in lakes, rivers, freshwater and aquatic life, Hg2+ can pass through the food chain, entering the human body and endangering health. Hg2+ detection has therefore become important thereby attracting extensive interests. Currently, several DNA-based sensors have been used for Hg2+ detection because they are not easy to degrade and are very stable. This paper summarizes the application of some DNA-based sensors based on fluorescence resonance energy transfer (FRET), analyzes their characteristic, and compares their sensitivity. Future perspectives and possible challenges in this area are also outlined.

Keywords: DNA-based sensors; Detection; High sensitivity; Mercury ion.

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