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Case Reports
. 2018 Sep 4;6(10):2011-2014.
doi: 10.1002/ccr3.1790. eCollection 2018 Oct.

Bleomycin-induced pulmonary toxicity and treatment with infliximab: A case report

Victor Ge  1 , Iouri Banakh  2 , Ravindranath Tiruvoipati  1   3 , Kavi Haji  1   3
Affiliations
Case Reports

Bleomycin-induced pulmonary toxicity and treatment with infliximab: A case report

Victor Ge et al. Clin Case Rep. .

Abstract

Given the current understanding of bleomycin-induced pneumonitis (BIP), the use of tumor necrosis factor alpha (TNF-α) inhibitors such as infliximab for late-stage disease appears to be of limited benefit. Further research regarding prevention and management of advanced BIP is required.

Keywords: bleomycin; infliximab; intensive care; pulmonary toxicity; respiratory failure; treatment outcome.

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Figures

Figure 1
Figure 1
CT chest demonstrating extensive consolidation and ground glass opacification
See this image and copyright information in PMC

References

    1. Sleijfer S. Bleomycin‐induced pneumonitis. Chest. 2001;120(2):617‐624. - PubMed
    1. Bleomycin product information document submitted to Therapeutic Goods of Australia, Aspen Pharma Pty Ltd, Published on June 26, 2006. https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&i.... Accessed June 24, 2018.
    1. Reinert T, Serodio da Rocha Baldotto C, Pereira Nunes F, Alves de Souza Scheliga A. Bleomycin‐induced lung injury. J Cancer Res. 2013;480608:9.
    1. Banakh I, Lam A, Tiruvoipati R, Carney I, Botha J. imatinib for bleomycin induced pulmonary toxicity: a case report and evidence‐base review. Clin Case Rep. 2016;4(5):486‐490. - PMC - PubMed
    1. Brugge SS, Claasen HR, Dawson L. Drug induced lung injury‐a case of fatal Bleomycin interstitial pneumonitis. Netherlands J Critical Care. 2013;17:25‐29.

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