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Editorial
. 2018 Nov;72(5):1087-1089.
doi: 10.1161/HYPERTENSIONAHA.118.11830.

PARP-1 (Poly[ADP-Ribose] Polymerase-1)

Rhéure Alves-Lopes  1 , Rhian M Touyz  1
Affiliations
Editorial

PARP-1 (Poly[ADP-Ribose] Polymerase-1)

Rhéure Alves-Lopes et al. Hypertension. 2018 Nov.
No abstract available

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Figures

Figure 1
Figure 1. Hypothetical scheme demonstrating possible mechanisms linking major molecular players whereby PARP-1 influences AAA formation.
We suggest that DNA damage and redox-regulated PARP1-influences ADPR-activated TRPM2, which induces Ca2+ influx and activation of signaling pathways in vascular cells that promote aneurysm formation.
See this image and copyright information in PMC

Comment on

References

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