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Review
. 2018:1077:225-249.
doi: 10.1007/978-981-13-0947-2_13.

Injectable Nanocomposite Hydrogels and Electrosprayed Nano(Micro)Particles for Biomedical Applications

Nguyen Vu Viet Linh  1   2 , Nguyen Tien Thinh  3   4 , Pham Trung Kien  1 , Tran Ngoc Quyen  5 , Huynh Dai Phu  6   7
Affiliations
Review

Injectable Nanocomposite Hydrogels and Electrosprayed Nano(Micro)Particles for Biomedical Applications

Nguyen Vu Viet Linh et al. Adv Exp Med Biol. 2018.

Abstract

Polymeric scaffolds have played important roles in biomedical applications due to their potentially practical performance such as delivery of bioactive components and/or regenerative cells. These materials were well-designed to encapsulate bioactive molecules or/and nanoparticles for enhancing their performance in tissue regeneration and drug delivery systems. In the study, several multifunctional nanocomposite hydrogel and polymeric nano(micro)particles-electrosprayed platforms were described from their fabrication methods and structural characterizations to potential applications in the mentioned fields. Regarding to their described performance, these multifunctional nanocomposite biomaterials could pay many ways for further studies that enables them apply in clinical applications.

Keywords: Biomedical applications; Electrospray; Injectable hydrogel; Nanocomposite; Polysaccharide.

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References

    1. Yuan Y, Lin D, Chen F, Liu C (2014) Clinical translation of biomedical materials and the key factors towards product registration. J Orthop Transl 2(2):49–55
    1. Li Y, Rodrigues J, Tomás H (2012) Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications. Chem Soc Rev 41(6):2193–2221 - PubMed - DOI
    1. Scaffaro R, Lopresti F, Maio A, Sutera F, Botta L (2017) Development of polymeric functionally graded scaffolds: a brief review. J Appl Biomater Funct Mater 15(2):107–121
    1. Schmaljohann D (2006) Thermo- and pH-responsive polymers in drug delivery. Adv Drug Deliv Rev 58(15):1655–1670 - PubMed - DOI
    1. Kurisawa M, Chung JE, Yang YY, Gao SJ, Uyama H (2005) Injectable biodegradable hydrogels composed of hyaluronic acid-tyramine conjugates for drug delivery and tissue engineering. Chem Commun 34:4312–4314 - DOI

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