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. 2019 Jan;94(1):E27-E29.
doi: 10.1002/ajh.25329. Epub 2018 Nov 29.

Hydroxyurea prevents onset and progression of albuminuria in children with sickle cell anemia

Rima S Zahr  1 , Jane S Hankins  2 , Guolian Kang  3 , Chen Li  3 , Winfred C Wang  2 , Jeffrey Lebensburger  4 , Jeremie H Estepp  2   5
Affiliations

Hydroxyurea prevents onset and progression of albuminuria in children with sickle cell anemia

Rima S Zahr et al. Am J Hematol. 2019 Jan.
No abstract available

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Conflict of interest statement

Conflict of Interest Disclosures

The other authors declare no competing financial interests.

Figures

Figure 1.
Figure 1.
Probability of developing the first albuminuria episode after the initiation of hydroxyurea in children with SC. Figure 1a: Cumulative Incidence of developing albuminuria post HU initiation by baseline HU initiation age of ≥ 10 years as compared to <10 years. Figure 1b: Cumulative Incidence of developing albuminuria post HU initiation by baseline albumin to creatinine ratio of ≥ 100mg/g as compared to <100 mg/g. Figure 1c: Cumulative Incidence of developing albuminuria post HU initiation by baseline age and albumin to creatinine ratio. P-values reported are compared to participants with baseline ACR ≥ 100mg/g and age ≥ 10 years. Baseline ACR ≥ 100mg/g and age < 10 years p=0.006, baseline ACR < 100mg/g and ≥ age 10 years p=0.001, and baseline ACR < 100mg/g and age < 10 years p=0.0006.
See this image and copyright information in PMC

References

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