Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics

Affiliations

¹ Department of Pharmacy, Hospital Tengku Ampuan Afzan, 25100 Kuantan, Pahang, Malaysia.
² Department of Anaesthesiology, Emergency and Critical Care Medicine, Intensive Care Unit, Nîmes University Hospital, place du Professeur Debré, 30029 Nîmes, France.
³ University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia; Centre for Translational Anti-Infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Australia; Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Australia. Electronic address: j.roberts2@uq.edu.au.

Editorial

Janattul-Ain Jamal et al. Anaesth Crit Care Pain Med. 2018 Dec.

. 2018 Dec;37(6):515-517.

doi: 10.1016/j.accpm.2018.10.006. Epub 2018 Oct 22.

¹ Department of Pharmacy, Hospital Tengku Ampuan Afzan, 25100 Kuantan, Pahang, Malaysia.
² Department of Anaesthesiology, Emergency and Critical Care Medicine, Intensive Care Unit, Nîmes University Hospital, place du Professeur Debré, 30029 Nîmes, France.
³ University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia; Centre for Translational Anti-Infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Australia; Departments of Pharmacy and Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Australia. Electronic address: j.roberts2@uq.edu.au.

No abstract available

Keywords: Critical illness; Drug dosing; Pathophysiologic; Pharmacokinetic.

Comment on

Sevoflurane for procedural sedation in critically ill patients: A pharmacokinetic comparative study between burn and non-burn patients.
Perbet S, Bourdeaux D, Lenoire A, Biboulet C, Pereira B, Sadoune M, Plaud B, Launay JM, Bazin JE, Sautou V, Mebazaa A, Houze P, Constantin JM, Legrand M; PRONOBURN group. Perbet S, et al. Anaesth Crit Care Pain Med. 2018 Dec;37(6):551-556. doi: 10.1016/j.accpm.2018.02.001. Epub 2018 Feb 15. Anaesth Crit Care Pain Med. 2018. PMID: 29455032