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Review
. 2018 Nov 26;47(23):8842-8880.
doi: 10.1039/c8cs00185e.

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

Adam C Sedgwick  1 , Luling Wu, Hai-Hao Han, Steven D Bull, Xiao-Peng He, Tony D James, Jonathan L Sessler, Ben Zhong Tang, He Tian, Juyoung Yoon
Affiliations
Review

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

Adam C Sedgwick et al. Chem Soc Rev. .

Abstract

In this review we will explore recent advances in the design and application of excited-state intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based sensors and imaging agents (probes) are important in biology, physiology, pharmacology, and environmental science for the selective detection of biologically and/or environmentally important species. The development of ESIPT-based fluorescence probes is particularly attractive due to their unique properties, which include a large Stokes shift, environmental sensitivity and potential for ratiometric sensing.

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