Brain Na+,K+-ATPase activity possibly regulated by a specific serotonin receptor
- PMID: 3036307
- DOI: 10.1016/0006-8993(87)90414-8
Brain Na+,K+-ATPase activity possibly regulated by a specific serotonin receptor
Abstract
Na+,K+-ATPase activity in 6 regions of adult brain was measured after incubation with varying concentrations of serotonin. A concentration-dependent increase in enzyme activity was observed in 4 regions, with cerebral cortex and cerebellum showing the largest response. These results together with previous ones suggest that serotonin modulates brain Na+,K+-ATPase activity through a specific receptor located in target neurons or glial cells.
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