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. 1987 Apr 7;408(1-2):399-402.
doi: 10.1016/0006-8993(87)90414-8.

Brain Na+,K+-ATPase activity possibly regulated by a specific serotonin receptor

J Hernández

Brain Na+,K+-ATPase activity possibly regulated by a specific serotonin receptor

J Hernández. Brain Res. .

Abstract

Na+,K+-ATPase activity in 6 regions of adult brain was measured after incubation with varying concentrations of serotonin. A concentration-dependent increase in enzyme activity was observed in 4 regions, with cerebral cortex and cerebellum showing the largest response. These results together with previous ones suggest that serotonin modulates brain Na+,K+-ATPase activity through a specific receptor located in target neurons or glial cells.

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