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Case Reports
. 2018 Jan 3;5(2):191-194.
doi: 10.1002/mdc3.12569. eCollection 2018 Mar-Apr.

Percutaneous Endoscopic Transgastric Jejunostomy (PEG-J) Tube Placement for Levodopa-Carbidopa Intrajejunal Gel Therapy in the Interventional Radiology Suite: A Long-term Follow-up

Maria Valeria Saddi  1 , Marianna Sarchioto  2   3 , Giulia Serra  1 , Daniela Murgia  2 , Valeria Ricchi  2 , Marta Melis  2   3 , Roberta Arca  2 , Pierpaolo Carreras  4 , Loredana Sitzia  4 , Sandro Zedda  5 , Giovanni Dui  5 , Rosario Rossi  1 , Anna Ticca  1 , Maurizio Melis  2 , Giovanni Cossu  2
Affiliations
Case Reports

Percutaneous Endoscopic Transgastric Jejunostomy (PEG-J) Tube Placement for Levodopa-Carbidopa Intrajejunal Gel Therapy in the Interventional Radiology Suite: A Long-term Follow-up

Maria Valeria Saddi et al. Mov Disord Clin Pract. .

Abstract

Background: Percutaneous endoscopic gastrojejunostomy (PEG) and radiologically inserted gastrojejunostomy (RIG) are both safe and effective techniques for gastrojejunal tube placement. The authors compared these 2 procedures in patients with advanced Parkinson's disease (PD) who required the continuous intrajejunal delivery of a levodopa/carbidopa gel suspension (LCIG).

Methods: Outcomes were retrospectively collated from 30 PEG and 12 RIG procedures performed at 2 centers in patients with advanced PD for the delivery of LCIG.

Results: Baseline clinical characteristics, incidence of early severe adverse events, late major complications, dropout, and the mean time-lapse of tube replacements were comparable in the PEG and RIG groups.

Conclusion: The current results suggest that, in patients with PD, the RIG technique is as safe and effective as the endoscopic procedure, and it can be considered a valid option for patients who require LCIG when the endoscopic procedure is not available or unfeasible.

Keywords: Parkinson's disease; endoscopic gastrojejunostomy; levodopa/carbidopa intestinal gel; percutaneous radiologic gastrojejunostomy.

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