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Case Reports
. 2016 May 18;2(2):20150201.
doi: 10.1259/bjrcr.20150201. eCollection 2016.

MRI of a recurrent adenoid cystic carcinoma of the trachea, treated with fast neutron therapy

Affiliations
Case Reports

MRI of a recurrent adenoid cystic carcinoma of the trachea, treated with fast neutron therapy

Laura Sweeney et al. BJR Case Rep. .

Abstract

Adenoid cystic carcinoma (ACC) of the trachea is a rare tumour, which responds well to high linear energy transfer radiation, such as neutron therapy. Both CT and MRI are useful for its diagnosis, with MRI being superior at determining the extent of disease and perineural involvement. Identification of these disease characteristics with MRI helps to determine lesion resectability and decide on the most appropriate treatment strategies. MRI is also useful in the differentiation of post-radiation change from disease recurrence, with post-radiation change displaying low T 2 signal intensity compared with tumour recurrence displaying intermediate to high T 2 signal intensity. Furthermore, MR diffusion-weighted imaging can be useful in the distinction between the two. We present a case of tracheal ACC treated with fast neutron therapy and followed with MRI.

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Figures

Figure 1.
Figure 1.
Contrast-enhanced MRI of the mediastinum: coronal slice. Block arrow: recurrent tumour, pre-treatment (November 2011). Broken arrow: level of previous surgical resection and end-to-end anastomosis.
Figure 2.
Figure 2.
Contrast-enhanced MRI of the mediastinum: axial slice. Block arrow: recurrent tumour, pre-treatment (November 2011).
Figure 3.
Figure 3.
Isodose demonstrating coverage of at least 95%, 5 mm from the clinical target volume.
Figure 4.
Figure 4.
Contrast-enhanced MRI of the mediastinum: axial slice. Block arrow: reduction in tumour size, 1 year post-treatment (November 2012).
Figure 5.
Figure 5.
Contrast-enhanced MRI of the mediastinum: axial slice. Block arrow: further reduction in tumour size, 3 years post-treatment (November 2014).

References

    1. Pearson FG, Cardoso P, Keshavjee S. Primary tumours of the upper airway In: Pearson FG, Deslauries J, Ginsberg RJ, eds. Thoracic surgery. 1st ed. New York, NY: Churchill Livingstone; 1995. 285–99.
    1. Urdaneta AI, Yu JB, Wilson LD. Population based cancer registry analysis of primary tracheal carcinoma. Am J Clin Oncol 2011; 34: 32–7. - PubMed
    1. Natarajan S, Greaves TS, Raza AS, Cobb CJ. Fine-needle aspiration of an adenoid cystic carcinoma of the larynx mimicking a thyroid mass. Diagn Cytopathol 2004; 30: 115–18. - PubMed
    1. Seaver PR, Kuehn PG. Adenoid cystic carcinoma of the salivary glands. a study of ninety-three cases. Am J Surg 1979; 137: 449–55. - PubMed
    1. Graham MV, Emami B. Mediastinum and trachea In: Perez CA, Brady LW, eds. Principles and practice of radiation oncology. 3rd ed. Philadelphia, PA: Lippincott-Raven; 1998. 1221–39.

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