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Case Reports
. 2014 May 19;1(2):125-127.
doi: 10.1002/mdc3.12036. eCollection 2014 Jun.

Perimenstrual Fluctuations in Two Siblings With Early-Onset Parkinson's Disease

Fabienne S Sprenger  1 , Klaus Seppi  1 , Elisabeth Wolf  1 , Werner Poewe  1
Affiliations
Case Reports

Perimenstrual Fluctuations in Two Siblings With Early-Onset Parkinson's Disease

Fabienne S Sprenger et al. Mov Disord Clin Pract. .
No abstract available

Keywords: Parkinson's disease; gestagen; premenopausal.

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Figures

Figure 1
Figure 1
Diaries of case I (A and B) and II (C and D) showing OFF time before (A and C) and while being on dienogest‐ethinylestradiol supplementation (B and D).
See this image and copyright information in PMC

References

    1. Quinn NP, Marsden CD. Menstrual‐related fluctuations in Parkinson's disease. Movement Disord 1986;1:85–87. - PubMed
    1. Thulin PC, Carter JH, Nichols MD, et al. Menstrual cycle related changes in Parkinson's disease. Neurology 1996;46:5128–5218.
    1. Blanchet PJ, Fang J, Hyland K, Arnold LA, Mouradian MM, Chase TN. Short‐term effects of high‐dose 17beta‐estradiol in postmenopausal PD patients: a crossover study. Neurology 1999;53:91–95. - PubMed
    1. Tsang KL, Ho SL, Lo SK. Estrogen improves motor disability in parkinsonian postmenopausal women with motor fluctuations. Neurology 2000;54:2292–2298. - PubMed
    1. Parkinson Study Group PI . A randomized pilot trial of estrogen replacement therapy in post‐menopausal women with Parkinson's disease. Parkinsonism Relat Disord 2011;17:757–760. - PubMed

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