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Review
. 2018 Oct 1:2018:3725837.
doi: 10.1155/2018/3725837. eCollection 2018.

Current Role of Chemotherapy in Nonmetastatic Nasopharyngeal Cancer

Tapesh Bhattacharyya  1 , Geethu Babu  2 , Cessal Thommachan Kainickal  2
Affiliations
Review

Current Role of Chemotherapy in Nonmetastatic Nasopharyngeal Cancer

Tapesh Bhattacharyya et al. J Oncol. .

Abstract

Nasopharyngeal carcinoma is highly radio- and chemosensitive tumor with its unique clinical and biological behavior. Treatment of stage I disease is radical radiotherapy alone. For stage II disease treatment is radiotherapy with or without chemotherapy. The standard of care for locally advanced nasopharyngeal cancer (stages III-IVB) is concurrent chemoradiation. Optimum timing and sequence of chemotherapy are not yet well-defined. The role of adjuvant and induction chemotherapy is debatable. Here we are going to highlight the role of chemotherapy in nasopharyngeal carcinoma, its benefit, and controversies regarding timing and sequences.

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