Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Aug 24;9(11):227-240.
doi: 10.1177/2040622318790197. eCollection 2018 Nov.

Epidemiology of sarcoidosis: current findings and future directions

Affiliations
Review

Epidemiology of sarcoidosis: current findings and future directions

Elizabeth V Arkema et al. Ther Adv Chronic Dis. .

Abstract

Sarcoidosis is a granulomatous inflammatory disease with unknown etiology. Epidemiological studies have contributed greatly to our knowledge about sarcoidosis, providing critical information on the determinants and distribution of the disease. In this review, we summarize recently published findings from epidemiological studies on sarcoidosis. We review the epidemiological tools used, the incidence and prevalence of disease, mortality and cancer risk after sarcoidosis and nongenetic risk factors for sarcoidosis. Genetics studies have not been included as they deserve a separate review. Leveraging existing epidemiological data to conduct etiological studies aimed towards understanding and preventing disease is critical for future sarcoidosis research.

Keywords: Epidemiology; Incidence; Mortality; Prevalence; Sarcoidosis.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest statement: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Incidence of sarcoidosis per 100,000 per year reported in the literature 2015–2017 categorized by ethnic group. *Studies from Olmsted County, MN (USA) and Sweden include populations who are majority (>90%) white. NHSII, Nurses’ Health Study II.

References

    1. Prasse A, Katic C, Germann M, et al. Phenotyping sarcoidosis from a pulmonary perspective. Am J Respir Crit Care Med 2008; 177: 330–336. - PubMed
    1. du Bois RM, Goh N, et al. Is there a role for microorganisms in the pathogenesis of sarcoidosis? J Intern Med 2003; 253: 4–17. - PubMed
    1. Aschengrau A SG. Essentials of epidemiology in public health. 3rd ed. Sudbury, MA: Jones and Bartlett, 2014.
    1. Baughman RP, Teirstein AS, Judson MA, et al. Clinical characteristics of patients in a case control study of sarcoidosis. Am J Respir Crit Care Med 2001; 164: 1885–1889. - PubMed
    1. Design of a case control etiologic study of sarcoidosis (ACCESS). ACCESS research group. J Clin Epidemiol 1999; 52: 1173–1186. - PubMed

LinkOut - more resources