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Case Reports
. 2018 Oct 10:35:189-191.
doi: 10.1016/j.amsu.2018.10.010. eCollection 2018 Nov.

Acute Acalculous Cholecystitis due to primary acute Epstein-Barr virus infection treated with laparoscopic cholecystectomy; a case report

Kamal N Rezkallah  1 , Khalid Barakat  1 , Abdurraheem Farrah  1 , Shesh Rao  1 , Monica Sharma  1 , Shyam Chalise  1 , Teresita Zdunek  2
Affiliations
Case Reports

Acute Acalculous Cholecystitis due to primary acute Epstein-Barr virus infection treated with laparoscopic cholecystectomy; a case report

Kamal N Rezkallah et al. Ann Med Surg (Lond). .

Abstract

Introduction: Epstein Barr virus (EBV) is a human herpes virus 4, transmitted through intimate contact between susceptible persons and asymptomatic EBV shedders. It usually presents with fever, pharyngitis and lymphadenopathy. Majority of individuals with primary EBV infection recover uneventfully. Acute Acalculous Cholecystitis (AAC) is usually seen in hospitalized and critically ill patients with major trauma, shock, severe sepsis, total parenteral nutrition and mechanical ventilation.

Case presentation: We report a 25-year- old woman presented with acute Epstein-Barr Virus (EBV)infection and hepatobiliary iminodiacetic acid (HIDA) scan confirmed presence of Acute Acalculous Cholecystitis (AAC). Conservative management was advised initially, but she had a laparoscopic cholecystectomy due to intolerable abdominal pain.

Conclusion: AAC is a rare complication of acute EBV infection and it is usually managed conservatively, although our patient had laparoscopic cholecystectomy due to intolerable abdominal pain.

Keywords: AAC, Acute Acalculous Cholecystitis; Acalculous; Case report; Cholecystitis; EBV; EBV, Epstein Barr virus; Epstein-Barr virus; Gallbladder; HIDA, Hepatobiliary iminodiacetic acid; SCARE, Surgical Case Report.

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Figures

Fig. 1
Fig. 1
HIDA scan showing non-accumulation of the isotope within the gallbladder.
See this image and copyright information in PMC

References

    1. Odumade O.A., Hogquist K.A., Balfour H.H., Jr. Progress and problems in understanding and managing primary Epstein-Barr virus infections. Clin. Microbiol. Rev. 2011;24:193–209. - PMC - PubMed
    1. Rafailidis Vouloumanou EK., Falagas ME P.I. Current diagnosis and management of infectious mononucleosis. Curr. Opin. Hematol. 2012;19:14–20. - PubMed
    1. Huffman J.L., Schenker S. Acute acalculous cholecystitis: a review. Clin. Gastroenterol. Hepatol. 2010;8:15–22. - PubMed
    1. Barie P.S., Eachempati S.R. Acute acalculous cholecystitis. Gastroenterol. Clin. N. Am. 2010;39:343–357. - PubMed
    1. Agha R.A., Fowler A.J., Saetta A., Barai I., Rajmohan S., Orgill D.P., for the SCARE Group The SCARE Statement: consensus-based surgical case report guidelines. Int. J. Surg. 2016;34:180–186. - PubMed

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