Database Resources of the BIG Data Center in 2019

Abstract

The BIG Data Center at Beijing Institute of Genomics (BIG) of the Chinese Academy of Sciences provides a suite of database resources in support of worldwide research activities in both academia and industry. With the vast amounts of multi-omics data generated at unprecedented scales and rates, the BIG Data Center is continually expanding, updating and enriching its core database resources through big data integration and value-added curation. Resources with significant updates in the past year include BioProject (a biological project library), BioSample (a biological sample library), Genome Sequence Archive (GSA, a data repository for archiving raw sequence reads), Genome Warehouse (GWH, a centralized resource housing genome-scale data), Genome Variation Map (GVM, a public repository of genome variations), Science Wikis (a catalog of biological knowledge wikis for community annotations) and IC4R (Information Commons for Rice). Newly released resources include EWAS Atlas (a knowledgebase of epigenome-wide association studies), iDog (an integrated omics data resource for dog) and RNA editing resources (for editome-disease associations and plant RNA editosome, respectively). To promote biodiversity and health big data sharing around the world, the Open Biodiversity and Health Big Data (BHBD) initiative is introduced. All of these resources are publicly accessible at http://bigd.big.ac.cn.

Figure 1.

The BIG Data Center’s core data resources. Three categories, viz. data, information and knowledge, are adopted to represent resources that are typically to deposit raw data/metadata (archives), house processed/analyzed data (libraries) and integrate validated knowledge (through literature curation; knowledgebases), respectively. A full list of data resources, which contains links to each resource, is available at http://bigd.big.ac.cn/databases.

Figure 2.

Statistics of data submissions to BioProject, BioSample and GSA. (A) Data statistics of BioProject and BioSample. (B) Data statistics of Experiments and Runs as well as file size in GSA. All statistics are frequently updated and publicly available at http://bigd.big.ac.cn/bioproject/, http://bigd.big.ac.cn/biosample/ and http://bigd.big.ac.cn/gsa/.