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Comment
. 2018 Oct;33(10):1560.
doi: 10.1002/mds.27496.

Th17 lymphocyte spearheads the immune attack in Parkinson's disease: New evidence for neuronal death

Aparna Wagle Shukla  1 , Susan H Fox  2
Affiliations
Comment

Th17 lymphocyte spearheads the immune attack in Parkinson's disease: New evidence for neuronal death

Aparna Wagle Shukla et al. Mov Disord. 2018 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of interest:

A Wagle Shukla: There is no conflict of interest

S Fox: There is no conflict of interest.

Comment on

References

    1. Ransohoff RM. How neuroinflammation contributes to neurodegeneration. Science 2016;353:777–783. - PubMed
    1. Sulzer D, Alcalay RN, Garretti F, et al. T cells from patients with Parkinson’s disease recognize alpha-synuclein peptides. Nature 2017;546:656–661. - PMC - PubMed
    1. Brochard V, Combadiere B, Prigent A, et al. Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J Clin Invest 2009;119:182–192. - PMC - PubMed
    1. Kannarkat GT, Boss JM, Tansey MG. The role of innate and adaptive immunity in Parkinson’s disease. J Parkinsons Dis 2013;3:493–514. - PMC - PubMed
    1. Sommer A, Maxreiter F, Krach F, et al. Th17 lymphocytes induce neuronal cell death in a human iPSC-based model of Parkinson’s disease. Cell Stem Cell 2018;23:123–131.e6. - PubMed