doi: 10.1016/0020-711x(87)90034-6.
D-galactosamine induced changes in rat liver plasma membranes lipid composition and some enzyme activities
- PMID: 3036613
- DOI: 10.1016/0020-711x(87)90034-6
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D-galactosamine induced changes in rat liver plasma membranes lipid composition and some enzyme activities
Int J Biochem.
1987.
Abstract
The influence of D-galactosamine administration on rat liver plasma membranes lipid composition, fluidity and some enzyme activities was investigated. D-Galactosamine was found to induce an increase of the total phospholipids, the cholesterol level and membrane rigidity. In liver plasma membranes of D-galactosamine-treated rats the exogenous phospholipase A2 activity was enhanced about 2 fold, whereas the endogenous activity was slightly decreased. No alteration of the neutral sphingomyelinase activity was observed.
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