doi: 10.1016/0020-711x(87)90072-3.
Stimulation of mitochondrial functions by glucagon treatment, starvation and by treatment of isolated mitochondria with glycogen-bound enzymes
- PMID: 3036619
- DOI: 10.1016/0020-711x(87)90072-3
Item in Clipboard
Stimulation of mitochondrial functions by glucagon treatment, starvation and by treatment of isolated mitochondria with glycogen-bound enzymes
Int J Biochem.
1987.
Abstract
Liver mitochondria isolated from rats starved overnight, or fed rats injected with glucagon, exhibited a similar increase of the respiration rate with succinate (by 30-40%) and glutamate plus malate (by 20-30%), as compared to mitochondria from control fed animals. The content of mitochondrial adenine nucleotides was elevated by 30-45% by glucagon treatment or starvation. Mitochondrial respiration and citrulline synthesis were stimulated by 30-40% when mitochondria isolated from fed rats were briefly preincubated with the extract from liver glycogen granules, ATP and MgCl2. This effect was abolished by heating the extract at 100 degrees C.
Similar articles
-
Stimulation of mitochondrial functions by glucagon treatment. Evidence that effects are not artifacts of mitochondrial isolation.Biochem J. 1983 Mar 15;210(3):819-27. doi: 10.1042/bj2100819. Biochem J. 1983. PMID: 6409079 Free PMC article.
-
On the nature of the stimulation by glucagon of citrulline synthesis in rat-liver mitochondria.FEBS Lett. 1982 Apr 19;140(2):270-2. doi: 10.1016/0014-5793(82)80911-3. FEBS Lett. 1982. PMID: 7084468 No abstract available.
-
Elevated intramitochondrial adenine nucleotides and mitochondrial function.Arch Biochem Biophys. 1983 May;223(1):85-94. doi: 10.1016/0003-9861(83)90574-x. Arch Biochem Biophys. 1983. PMID: 6222697
-
The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria.Biochem J. 1980 Aug 15;190(2):293-300. doi: 10.1042/bj1900293. Biochem J. 1980. PMID: 7470052 Free PMC article.
-
The stimulatory effect of glucagon and dibutyryl cyclic AMP on ureogenesis and gluconeogenesis in relation to the mitochondrial ATP content.FEBS Lett. 1977 Aug 15;80(2):443-8. doi: 10.1016/0014-5793(77)80494-8. FEBS Lett. 1977. PMID: 196940 No abstract available.