Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP
- PMID: 3036689
- DOI: 10.1007/BF00283625
Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP
Abstract
Fibroblasts from a fetus with an unbalanced karyotype 46(XY), -16,+(16qter-16p13.3::4q31.1-4qter) were found to possess only one allele at the 3' hypervariable region (3'HVR) close to the alpha-globin locus and two alleles at the PGP locus. This places the alpha-globin locus at the very tip of 16p, distal to PGP.
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