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. 2018 Jun;8(6):510-514.
doi: 10.1038/s41558-018-0161-6. Epub 2018 May 21.

Antibiotic Resistance Increases with Local Temperature

Derek R MacFadden #  1   2   3 , Sarah F McGough #  2   4 , David Fisman  1 , Mauricio Santillana  3   4   5 , John S Brownstein  3   4   5
Affiliations

Antibiotic Resistance Increases with Local Temperature

Derek R MacFadden et al. Nat Clim Chang. 2018 Jun.
No abstract available

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Figures

Figure 1
Figure 1. Antibiotic resistance increases with increasing temperature.
(A) A heatmap of mean normalized antibiotic resistance for E. coli for all antibiotics across the United States. (B) A heatmap of 30-year average minimum temperature (°C) across the United States. (C) A scatter plot of antibiotic resistance versus minimum temperature (°C) by acquisition type for E. coli and amoxicillin. Unadjusted weighted linear trend line is shown in blue. (D) Slope of unadjusted relationship (% Resistance/°C) between minimum temperature and antibiotic resistance by antibiotic for E. coli. Antibiotic class coded by color shading.
Figure 2
Figure 2. Change in the relationship between minimum temperature and antibiotic resistance over time.
(A) Mean normalized antibiotic resistance versus minimum temperature (°C) for all pathogens and antibiotics, stratified by year (2013–2015). Unadjusted weighted linear relationships for years 2013–2015 are shown. (B) Mean normalized antibiotic resistance versus minimum temperature (°C) for all pathogens and antibiotics, stratified by year and route (oral versus IV). (C) Density distributions of association measures (slopes) between antibiotic resistance and minimum temperature, stratified by time and with median densities (by year) marked by vertical dashed lines
See this image and copyright information in PMC

References

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