doi: 10.1080/02681218780000171.
Itraconazole treatment of experimental systemic candidiasis in male rats
- PMID: 3037058
- DOI: 10.1080/02681218780000171
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Itraconazole treatment of experimental systemic candidiasis in male rats
J Med Vet Mycol.
1987 Apr.
Abstract
After intravenous infection with Candida albicans, rats received daily doses of itraconazole for 3 days. All rats receiving 2.5 mg kg-1 day-1 survived while all rats receiving sham-treatment died. With subsequent reduction of the itraconazole dose to 0.63 mg kg-1 day-1, no survival occurred and mortality rates equalled those of the control group.
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